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Semax

Semax

Price range: $45.00 through $65.00

Semax is a synthetic heptapeptide derived from the 4-10 fragment of adrenocorticotropic hormone (ACTH), with an added Pro-Gly-Pro tripeptide tail for improved stability. It was first described in the late 1980s. The molecule has the sequence Met-Glu-His-Phe-Pro-Gly-Pro, a molecular weight of approximately 826.92 g/mol, and the molecular formula C38H54N12O9. It dissolves readily in water and is supplied as a lyophilized powder. The Pro-Gly-Pro tail is a structural feature designed to resist breakdown by prolyl endopeptidases, giving Semax greater stability than the native ACTH fragment. CAS: 80714-61-0. This product is strictly for research purposes only.

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USA manufactured · USA tested · Ships from Gilbert, AZ
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USA Lab Tested
Ships from Gilbert, AZ
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Certificate of Analysis

Independent laboratory testing confirms purity and composition

99.267%
Purity
B0526
Batch
March 2026
Date
View Certificate →

Overview

Semax is a synthetic heptapeptide — a chain of seven amino acids — with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. It was first described in the late 1980s. Structurally, Semax is derived from a fragment of adrenocorticotropic hormone (ACTH), specifically the 4-10 segment, with an added Pro-Gly-Pro tripeptide tail that increases resistance to enzymatic degradation compared to the unmodified ACTH fragment.

The compound has a molecular formula of C37H51N9O10S (free acid form) and a molar mass of approximately 813.93 g/mol (826.92 g/mol as the acetate salt commonly supplied). It is water-soluble and supplied as a white to off-white lyophilized powder. Its CAS registry number is 80714-61-0. The Pro-Gly-Pro extension is a known structural motif used in peptide chemistry to resist cleavage by prolyl endopeptidases, distinguishing it structurally from the native ACTH(4-10) fragment.

This product is strictly for research purposes only. Not approved for human or animal use.

PubChem Reference: View compound profile on NIH PubChem

Key Characteristics

MOLECULAR PROFILE

Formula: C38H54N12O9

Molar Mass: 826.92 g/mol

CAS: 80714-61-0

Sequence: Met-Glu-His-Phe-Pro-Gly-Pro

PHYSICAL PROPERTIES

Form: White to off-white lyophilized powder

Solubility: Water-soluble

Storage: Requires refrigeration after reconstitution

Stability: Stable in lyophilized form

Weight 0.08 lbs
Dimensions 0.87 × 1.18 × 0.87 in
Size

5mg, 10mg
SKU: OATH-SEMAX Categories: , Tag:
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